Panagiotis Katsonis

Assistant Professor

Panagiotis Katsonis

Ph.D.
Assistant Professor

Panos is the developer of the Evolutionary Action method that estimates the functional and clinical impact of genetic variants. His research focuses on using Evolutionary Action to interpret any protein coding variants, either they come from human samples, animals, plants, or microorganisms. Panos has won multiple awards in international competitions organized by the CAGI community for the superior performance of the Evolutionary Action amongst the current state-of-the-art methods in the field. In 2000, Panos received his diploma in Chemical Engineering from NTUA in Greece, and in 2006, he received his PhD in Chemical and Biomolecular Engineering from University of Houston. Since 2006, he has been a part of the Lichtarge lab.

Publications

  • Koire A, Katsonis P, Lichtarge O, "REPURPOSING GERMLINE EXOMES OF THE CANCER GENOME ATLAS DEMANDS A CAUTIOUS APPROACH AND SAMPLE-SPECIFIC VARIANT FILTERING."
  • Katsonis P, Lichtarge O, "A formal perturbation equation between genotype and phenotype determines the evolutionary action of protein coding variations on fitness."
  • Katsonis P*, Koire A*, Wilson SJ*, Hsu TK, Lua RC, Wilkins AD, Lichtarge O, "Single nucleotide variations: Biological impact and theoretical interpretation."
  • Katsonis P, Lichtarge O, "Objective assessment of the evolutionary action equation for the fitness effect of missense mutations across CAGI-blinded contests."
  • Clarke CN, Katsonis P, Hsu TK, Koire AM, Silva-Figueroa A, Christakis I, Williams MD, Kutahyalioglu M, Kwatampora L, Xi Y, Lee JE, Koptez ES, Busaidy NL, Perrier ND, Lichtarge O, "Comprehensive genomic characterization of parathyroid cancer identifies novel candidate driver mutations & core pathways"
  • Katsonis P,Lichtarge O., "CAGI5: Objective performance assessments of predictions based on the Evolutionary Action equation."